Adenoma detection was not improved with increased pixelation alone or with the addition of chromoscopy.
Investigators in France recently completed a randomized controlled trial that was the first to compare high-resolution colonoscopy with standard colonoscopy and the third to compare chromoendoscopy with standard white-light endoscopy. The study involved 203 patients (mean age, 58) with family or personal histories of colonic neoplasia or with alarm symptoms after age 60. Patients were randomized to undergo colonoscopy with a standard-resolution colonoscope (≤410,000 pixels) or a high-resolution colonoscope (850,000 pixels). In the latter group, each colonic segment was examined with and without indigo carmine dye spray.
The total number of adenomas detected per patient with high-resolution colonoscopy and chromoscopy (HRC) was similar to the…