What Is the Optimal Approach to Managing Dyspepsia?

In comparison studies, investigators found that two treatment schemes, the step-up approach and the test-and-treat approach, had the most benefits in the treatment of dyspepsia.

Dyspepsia is a common complaint, and its optimal management remains undetermined. Consensus statements and practice guidelines from different sources give differing advice. Now, in two separate studies, investigators have compared the efficacy and cost-effectiveness of several approaches to treating dyspepsia.

In the first study, U.K. investigators recruited 762 patients who were randomized to one of four approaches: early endoscopy; testing for Helicobacter pylori infection followed by referral to endoscopic treatment (test and refer); testing followed by H. pylori eradication treatment (test and treat); or empiric proton-pump inhibitor (PPI) therapy for all patients with dyspepsia, regardless of H. pylori status. Patients with H. pylori in…

Reviewing Author

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose