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Prior studies have shown an association between dyspepsia and endoscopic findings in patients referred for endoscopy. To find out whether this association applies to the general population, investigators conducted a community-based trial involving 1033 participants — with or without dyspeptic symptoms — from two Italian villages. All participants completed gastrointestinal-symptom questionnaires and underwent urea breath testing for Helicobacter pylori infection and endoscopic examinations with biopsies for rapid urease testing and histological evaluation. The main results were as follows:
53.4% of participants were asymptomatic, 27.6% reported dyspepsia with or without prominent reflux symptoms, 10.5% reported prominent reflux symptoms with…