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Multiple population-based studies have suggested that the incidence of upper gastrointestinal (GI) bleeding and complications of peptic ulcer disease have decreased during the past several decades. However, similar data are not readily available for lower GI bleeding.
In 2009, investigators reported trends for upper and lower GI complications based on data collected retrospectively from 10 general hospitals in Spain from 1996 to 2005 (Am J Gastroenterol 2009; 104:1633). Now, these researchers report changes in incidence of hospitalization during the same 10-year period for the following events:
Upper GI bleeding incidence decreased from 54.6 to 25.8 per 100,000 population.
Upper GI perforation incidence decreased from 3.9 to 2.9 per 100,000.
Co…