Computer-Assisted Personalized Sedation for Endoscopy

A computer-assisted personalized sedation (CAPS) device delivers a fentanyl bolus followed by a propofol infusion to achieve moderate sedation in patients undergoing endoscopy. To avoid deep sedation and subsequent interruption of propofol administration, patients are monitored through vital signs, oximetry, and capnography and are tested for responses to frequent audio stimuli.

To investigate the safety and efficacy of CAPS compared with traditional sedation for endoscopy, researchers conducted an industry-funded, randomized, open-label, multicenter, parallel trial involving 1000 patients who underwent routine endoscopy from endoscopist/nurse teams without anesthesiologists present. Both groups first received 2 L/minute of supplemental oxyg…