Loading...
Ulcerative colitis and Crohn colitis are widely acknowledged risk factors for development of colorectal cancer (CRC). However, results of population-based studies have suggested that the risk is overestimated (JW Gastroenterol May 9 2006 and World J Gastroenterol 2008; 14:3937), which might arise from research conducted in referral centers, where patients have more-severe or more-extensive inflammatory bowel disease (IBD).
To assess the risk for CRC among patients with IBD in a broader patient population, researchers conducted a nested case-control study in all 93 general hospitals in the Netherlands. Cases were identified through a nationwide network and registry of histo- and cytopathology reports; controls, chosen from 22 randomly selecte…