Esophageal Adenocarcinoma in Populations with Gastroesophageal Reflux Disease

Incidence of EAC in patients with GERD was very low overall, especially among men younger than 50 and women at any age.

The incidence of esophageal adenocarcinoma (EAC) has increased rapidly during the past few decades. National society guidelines recommend endoscopic screening for Barrett esophagus in patients with long-standing gastroesophageal reflux disease (GERD). However, the incidence for EAC in demographic subpopulations with GERD is unknown.

To estimate the age- and gender-specific incidences of EAC among non-Hispanic whites with GERD in the U.S., researchers created a Markov computer model using readily available national surveillance data. To place the results in context, they cited incidences of breast cancer and colorectal cancer (CRC), for which screening recommendations are well established.

Incidence was lower for women than for men. At any age…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors