Alcohol Use and Esophageal Adenocarcinoma

Alcohol consumption did not increase the risk for adenocarcinoma of the esophagus or esophagogastric junction.

During the past 3 decades, incidence rates of esophageal adenocarcinoma (EAC) and esophagogastric junction cancer (EGJC) in the U.S. have increased more than any other solid tumor. The epidemiologic factors associated with these increases are not clearly defined.

To determine whether heavy alcohol intake — an established risk factor for esophageal squamous cell cancer — is also associated with EAC or EGJC, researchers analyzed pooled data from nine case-control and two cohort studies of the international Barrett's and Esophageal Adenocarcinoma Consortium (BEACON) involving a total of 3658 patients (1821 with EAC, 1837 with EGJC) and 10,854 controls among non-Hispanic white participants. Definition of a single drink was standardized across st…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors