Acute Kidney Injury Predicts Mortality in Acute Alcoholic Hepatitis

New criteria for renal failure are superior to traditional criteria in predicting 90-day mortality and should be put to use in clinical settings.

Acute alcoholic hepatitis (AH) is associated with significant morbidity and mortality. Traditionally, patients with AH with serum creatinine levels >1.5 mg/dL are considered to have poor prognoses. Recently, a new term has been developed for acute renal failure (acute kidney injury [AKI]) and is defined as an abrupt reduction (within 48 hours) in renal function that results in an absolute increase of serum creatinine of 0.3 mg/dL (or a 50% increase) from baseline. The increased short- and long-term mortality risk associated with AKI has been evaluated and validated in patients with several conditions but not acute AH.

To assess AKI and its prognostic value in patients with acute AH, investigators retrospectively examined detailed clinical an…

Reviewing Author

Atif Zaman, MD, MPH

Disclosures

Nothing to disclose

Atif Zaman, MD, MPH

Disclosures

Nothing to disclose

Acute Kidney Injury Predicts Mortality in Acute Alcoholic Hepatitis

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Reviewing Author