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This study addressed two questions: Does weight loss improve the symptoms of obstructive sleep apnea (OSA), and is the development or persistence of OSA an independent risk factor for metabolic abnormalities? The investigators used data from a cohort of obese individuals in the Swedish Obesity Subjects (SOS) study: 1592 underwent weight-loss surgery and 1431 underwent conservative (dietary) treatment. Follow-up lasted 2 years. The presence of OSA was inferred from questionnaires; blood pressure, cholesterol, triglycerides, and glucose were measured.
The surgical group lost substantial weight (mean, 27.8 kg), while the control group had little weight change. When the entire cohort was considered, a close association existed between weight los…