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Essential tremor (ET) is generally progressive and sometimes disabling, but it is presumed not to affect mortality. These authors conducted a prospective investigation of mortality rates in ET as part of a longitudinal, population-based survey of people older than 65 living in three small communities in Spain.
Two thirds of the original baseline participants were included in the analysis: 201 patients with ET and 3337 controls. During some 3 years of follow-up, 16.4% of the ET patients died, compared with 13.9% of the controls. In an adjusted Cox proportional-hazard model, risk for death was significantly increased for those with ET compared with controls (relative risk, 1.45). In the subset of patients and controls with follow-up longer tha…