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Migraine recently has been associated with an increased risk for ischemic stroke and myocardial infarction, but the mechanisms underlying this association remain unknown. In this population-based study, investigators examined whether migraine was associated with greater progression of atherosclerosis in the carotid and femoral arteries (ascertained by ultrasound every 5 years for 15 years). They also examined whether migraine was associated with a hypercoagulable state, indicated by lifetime risk for venous thromboembolism (VTE). Participants were 574 adults (age range, 40–79 at baseline).
Of the 574 participants, 111 had migraine. Contrary to expectations, the prevalence, severity, and 5-year progression of atherosclerosis did not differ si…