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A new review article uses the case of a woman with diabetic neuropathy as the cornerstone for a discussion of the nomenclature, epidemiology, clinical presentation, differential diagnosis, mechanisms of action, and treatment options for this condition.
As the author notes, focal diabetic neuropathies involve one nerve, whereas diffuse neuropathies involve more than one nerve. The most common diffuse diabetic neuropathy is diabetic polyneuropathy, with a prevalence between 28% and 55%. In diabetic polyneuropathy, sensory fibers are affected more than motor fibers. Some patients with diabetic polyneuropathy remain asymptomatic, but many present with painful, burning feet or numbness or weakness of the lower extremities.
The author also discusse…