A systematic review and meta-analysis provides a useful summary of treatments for brain arteriovenous malformations but also highlights how little we know about optimal management.
Brain arteriovenous malformations (AVMs) can be treated with surgical resection, focused irradiation (stereotactic radiosurgery), or endovascular embolization. To better understand and compare the outcomes of these treatment options, researchers performed a systematic review and meta-analysis of studies reporting follow-up results after AVM treatment.
For inclusion, studies had to report the duration of follow-up and rates of death and intracerebral hemorrhage in at least 15 consecutive patients undergoing treatment for ruptured or unruptured brain AVMs. Case fatality was defined as death during treatment or follow-up; hemorrhage rates included only events occurring more than 30 days after treatment.
The authors identified 137 articles report…
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DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)