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To create a prediction rule for the development of delirium during intensive care unit (ICU) stays, researchers assessed predictors among 1613 adult medical and surgical ICU patients at a single institution. They validated the prediction rule in 1443 other patients at the same hospital and at four other institutions in the Netherlands. They also compared the rule's performance against prediction of delirium by ICU nurses and physicians. To identify delirium, ICU nurses assessed patients three times daily using a standard, valid assessment tool with good interrater reliability.
Delirium developed at a rate of 30% in the cohort as a whole. The prediction rule consisted of 10 characteristics readily available on admission to the ICU. The rule s…