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Researchers conducted a randomized trial to test whether imaging-based identification of stroke patients with potentially salvageable brain tissue can improve outcomes of endovascular therapy.
Researchers used multimodal computed tomography or magnetic resonance imaging within 8 hours after stroke symptoms began in 118 patients, to predict which patients would have final infarcted tissue volume of 90 mL or less and 70% or less of the total ischemic area (a “favorable penumbral pattern”). The researchers randomized all patients to embolectomy with a first-generation device (with or without thrombolysis before or afterward) or to standard care.
Counter to expectations, identification of a favorable penumbral pattern did not improve outcomes of …