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Interest in the nonpharmacological treatment of headaches has led to several studies using neurostimulation techniques for the acute and preventive treatment of primary headache disorders such as migraine. In this study, researchers randomized 67 patients with ≥2 medically untreated migraine headaches per month, to either noninvasive transcutaneous electrical nerve stimulation (16 mA/60 Hz) of the supraorbital nerve (verum stimulation) or sham stimulation (1 mA/1 Hz). After a 1-month run-in period (baseline), patients were instructed to use neurostimulation for 20 minutes daily for 3 months. Stimulation with biphasic rectangular impulses was administered by a self-adhesive electrode placed on the forehead on the dermatome of the supratrochl…