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To investigate possible connections among depression, self-injury, and suicide attempt in teenagers, researchers comprehensively interviewed 164 adolescents with major depression enrolled in a treatment study of cognitive-behavioral therapy added to selective serotonin reuptake inhibitors and specialist care (JW Psychiatry Jul 20 2007). Participants were asked about nonsuicidal self-injury in the month before baseline (prebaseline) and after 28 weeks of treatment and about previous-month depressive symptoms, including suicidal ideation, at 6, 12, and 28 weeks.
Independent predictors of suicide attempts at 28 weeks included high suicidal ideation ratings, prebaseline nonsuicidal self-injury, and impaired family functioning. Predictors of nons…