Loading...
Some investigators have posited that premature or accelerated aging occurs in patients with schizophrenia, which has been associated with premature death and with age-related features, including reduced telomere content, lower levels of stromal cell–derived factor 1α (critical for healthy functioning of adult stem cells), increased interleukin-6, abnormal glucose tolerance, and high pulse pressure. These investigators examined testosterone levels, which usually start to decline in the 20s.
Participants were 33 drug-naive men with nonaffective psychosis and 33 comparison men; the groups were matched for age, body-mass index, smoking, blood cortisol levels, and socioeconomic status. Overall, total testosterone correlated negatively with age an…