A study of nutrient biomarker levels in plasma confirms the usual suspects that help or hurt our cognition.
Many studies have suggested that dietary factors, including specific nutrients, the Mediterranean diet, and obesity, are important in cognition. However, the data obtained are usually from questionnaires that rely on recall of food intake. These investigators examined plasma nutrient biomarkers of diet in 104 participants in a brain aging study (mean age, 87; 62% women).
The investigators constructed several nutrient biomarker patterns (NBPs) and assessed the relationships of NBPs to findings from neuropsychological tests and volumetric magnetic resonance imaging (in 42 patients). Of the group, 10% were carriers of the APOE4 gene, 21% had depression, and 44% had hypertension.
Several NBPs were associated with outcomes. A profile high in plasm…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)