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High rates of alcohol use disorders (AUDs) among patients with bipolar disorders warrant examination of possible risk factors. These researchers conducted randomized, double-blind, cross-over trials of responses to a fruit drink plus alcohol or plus placebo (alcohol aroma was added to placebo). The participants were 20 young men (ages, 18–21) with broad bipolar phenotype (BBP) and 20 healthy controls matched for age and alcohol intake. BBP participants had scored 7 or higher on the Mood Disorders Questionnaire (3 people had bipolar disorder II or not otherwise specified), and controls had scored 0. The alcohol and placebo trials occurred separately, 1 week apart.
BBP participants had greater expectations (e.g., relaxation, arousal) than cont…