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Obesity and physical inactivity predispose people to glucose intolerance and type 2 diabetes; thus, it makes sense to ask whether diabetes can be prevented by dietary changes and exercise. Finnish researchers identified 522 middle-aged, overweight people with impaired glucose tolerance (2-hour plasma glucose after glucose load, 140-200 mg/dL; fasting plasma glucose, <140 mg/dL) but without overt diabetes. The participants were randomly assigned to 1 of 2 groups: An intervention group received individually detailed advice on caloric restriction, fat restriction, increased fiber intake, and exercise (with close follow-up); in contrast, a control group received only general information on diet and exercise. Mean duration of follow-up was 3.2 y…