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Although the Human Genome Project has made an enormous contribution to our knowledge, the search for disease-related genes still is daunting. An era of “personalized genomics,” in which people would know the drugs to which they were most likely to respond and the diseases to which they were most vulnerable, seemed to be a long way off, because, until recently, it would take many months and would cost US$10–25 million to sequence a single person’s genome. In just the past few months, however, new technologies have been discovered — the HapMap (Journal Watch Nov 4 2005) and rapid gene sequencing (Journal Watch Oct 4 2005, and Science 2005 Sep 9;309:1728) that will greatly speed progress in individualized gene mapping and personalized genomes.…