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Catheter-related bloodstream infections are a preventable cause of morbidity and mortality. In this study, 67 hospitals in Michigan — accounting for 85% of intensive care unit (ICU) beds in that state — participated in a statewide patient safety initiative, one component of which was to reduce rates of central venous catheter–related bloodstream infections in the ICU.
Each hospital systematically implemented and monitored a set of five interventions in its ICUs: hand washing, using full-barrier precautions during insertion of central venous catheters, cleansing the catheter insertion site with chlorhexidine, avoiding femoral vein catheter sites, and removing unnecessary catheters. Before the intervention, the median rate of catheter-related …