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Guidelines recommend initial screening for osteoporosis at age 65, and in current practice, clinicians commonly repeat bone-mineral density (BMD) measurements every few years. In a prospective study of 4124 women aged 65 and older, researchers assessed the value of repeating BMD measurement 8 years after a baseline measurement for predicting fracture risk. Subjects were contacted by postcard every 4 months to determine whether they had experienced a hip or nonspine fracture; positive responses were adjudicated by reviewing radiology reports. Given that the study was designed to evaluate the value of repeat BMD measurements in predicting fracture risk, fractures that occurred before the second BMD evaluation were excluded from the analysis.
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