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The controversy continues about whether aspirin should be prescribed for primary prevention of cardiovascular disease (CVD) and cancer in women. Researchers evaluated the risk for death from CVD or cancer among 79,439 women (mean age, 46; 97% white) in the prospective Nurses’ Health Study. Participants were followed biennially and classified according to aspirin use.
During 24 years of follow-up, 6460 deaths were attributed to CVD or cancer. In multivariate analyses, the risks for death from CVD or cancer were significantly lower among current users of aspirin than among women who never used aspirin regularly (relative risks, 0.62 and 0.88, respectively). The association between aspirin use and lower cardiovascular mortality was evident with…