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In earlier studies, the accuracy of computed tomographic colonography (CTC) screening has varied compared with conventional colonoscopy. This latest study from the University of Wisconsin compared two groups: In a “primary CTC” group, 3120 people underwent initial CTC screening, and those with polyps of at least 6 mm were offered colonoscopy the same day; in a “primary colonoscopy” comparison group, 3163 people directly underwent colonoscopy. Patients were not randomized but rather were referred by physicians for one procedure or the other. Mean age and male/female ratio were similar in the two groups.
Only 8% of CTC patients proceeded to colonoscopy; thus, many fewer polyps were removed in the primary CTC group than in the primary colonosco…