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The growing prevalence of obesity, and the known association of overweight (as well as underweight) with higher all-cause mortality rates, led U.S. investigators to explore the relation between cause-specific mortality and body-mass index; they examined standardized national health-status surveys starting in 1971, with follow-up through 2004.
Underweight (BMI, <18.5 kg/m2) was associated with significantly higher mortality from noncancer, noncardiovascular disease (non-CVD) causes, whereas overweight (BMI, 25–<30) actually was associated with significantly lower mortality from those causes. Neither underweight nor overweight was associated with any difference in mortality from cancer or CVD causes. However, obesity (BMI, ≥30) was associated …