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How well does physical examination identify patients with subclinical peripheral vascular disease? To answer this question, French researchers analyzed data from a cohort study of 2736 adults (mean age, 52) with no clinical histories of coronary, cerebrovascular, or peripheral vascular disease. A single physician examined all patients (with attention to the vascular system), and all patients underwent carotid ultrasound and measurement of ankle-brachial index (ABI).
The examiner found carotid bruits in 4% of patients, femoral bruits in 4%, and absence of ipsilateral dorsalis pedis and posterior tibial pulses in 3%. Presence of a femoral bruit predicted an abnormal ipsilateral ABI (odds ratio, 3.0, after adjustment for 10-year Framingham coro…