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The realization that celiac disease (CD) is far more common than once thought makes understanding its clinical presentation more important. Investigators from the Children’s Hospital of Wisconsin reviewed the medical records of all 143 patients (age range, 1–17 years) who received CD diagnoses over a 17-year period.
The number of cases diagnosed rose significantly year by year, from 1 in 1986 to 93 in 2003, as did mean patient age, from 5.3 years before 1995 to 8.7 years after 1995. The most common nongastrointestinal conditions associated with CD were type 1 diabetes (n=56), thyroiditis (n=15), short stature (n=13), Down syndrome (n=11), family history of CD (n=10), and iron deficiency (n=9). GI conditions that led to the diagnosis included…