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Particulate air pollution is associated with excess risks for heart disease and stroke. In a case-control study, conducted in northern Italy, researchers assessed whether such pollution also might be linked to venous thrombosis. A total of 871 patients who were diagnosed between 1995 and 2005 with lower-limb deep venous thrombosis (DVT) and 1210 healthy controls were enrolled in the investigation. The researchers estimated participants’ exposure to particulate-matter air pollutants <10 µm in diameter (PM10) during the year before DVT diagnosis (cases) or examination (controls), based on monitored levels of PM10 in nine geographic regions.
Mean PM10 exposure during the year before diagnosis or examination varied by region, ranging from 12 to …