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Sleep deprivation is thought to be associated with elevated risk for coronary artery disease, but most studies have relied on self-reported sleep data. Researchers in this observational cohort study took a novel approach: 495 healthy middle-aged people (mean age, 40) with no calcification on baseline electron beam computed tomography (EBCT) went to bed wearing wrist accelerometers that tracked their movements. Subjects were assessed for a wide range of clinical variables and risk factors, and EBCT was repeated at 5 years.
At follow-up EBCT, 61 people (12%) had new coronary artery calcifications. In an analysis that was adjusted for CAD risk factors, the likelihood of subjects developing incident coronary artery calcification was lower by rou…