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The “open-artery hypothesis” holds that percutaneous coronary intervention (PCI) might be beneficial for a patient whose infarct-related artery is totally occluded several days after myocardial infarction. However, in a randomized trial published in 2006, PCI with stenting — performed 3 to 28 days after MI — did not lower 4-year incidence of death, recurrent MI, or severe heart failure among such patients (JW Dec 13 2006). Now, the investigators report outcomes related to quality of life.
At 4 months, the mean score on a functional status index was modestly, but significantly, higher in the PCI group than in the medical-therapy group; however, differences between groups disappeared by 12 and 24 months. Proportions of patients with angina wer…