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The American Diabetes Association (ADA) recommends screening for diabetes every 3 years in all asymptomatic overweight adults with at least one additional risk factor and in all adults starting at age 45. But alternative screening strategies have not been rigorously compared.
Researchers used a well-validated mathematical model — representing normal physiology, a wide range of morbidities and health-related interventions, and random variation — to compare no screening with eight diabetes screening strategies in a simulated population of 325,000 nondiabetic people (age, 30) who were followed for 50 years. Representative U.S. health data were used to create the simulated population. Screening strategies ranged from no screening to maximum scre…