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Coronary artery calcium (CAC) scores as assessed by computed tomography correlate with burden of atherosclerosis and risk for future adverse coronary events. In this analysis, U.S. investigators examined a cohort of 5878 ethnically diverse patients without known atherosclerosis or diabetes to assess whether CAC scoring at baseline, added to traditional risk factors, allowed reclassification of patients into higher- or lower-risk groups for subsequent adverse cardiac events.
Of 209 events that occurred during 6 years of follow-up, 122 were death, myocardial infarction, or resuscitated cardiac arrest. Patients were categorized as low (5-year risk, 0%–<3%), intermediate (3%–10%), and high (>10%) risk for incident adverse cardiac events by demog…