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Because intranasal steroids are the most effective medications for allergic rhinitis symptoms (especially congestion), guidelines recommend them as first-line agents for moderate-to-severe disease. As many as 85% of patients with seasonal allergic rhinitis also have ocular symptoms. For these patients, many clinicians prescribe oral antihistamines or ocular products rather than (or in addition to) intranasal steroids.
In an industry-sponsored randomized trial, 429 patients with seasonal allergic rhinitis received once-daily mometasone furoate nasal spray (200 μg) or placebo spray for 15 days. Compared with the placebo group, the mometasone group exhibited statistically and clinically significant improvement in both nasal and ocular symptoms.…