Loading...
In a nationwide cohort study, Swedish investigators assessed whether systolic blood pressure (SBP) and diastolic blood pressure (DBP) during late adolescence are associated with early mortality.
Participants were 1.2 million young Swedish men (mean age, 18) who underwent physical examinations at military conscription between 1969 and 1995. During median follow-up of 24 years, 29,000 men (2.4%) died. Multivariate regression models showed a relation between SBP and total mortality that was U-shaped — risk was lowest at an SBP of about 130 mm Hg and highest at the extremes of SBP. The U-shaped pattern was explained by rising noncardiovascular mortality at lower SBP and rising cardiovascular mortality at higher SBP, particularly at >120 mm Hg. T…