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Several psychosocial factors, including stress, have been associated with elevated risk for coronary heart disease (CHD). In this study, researchers evaluated whether long working hours predict CHD risk beyond that provided by the Framingham risk model. Data on the working hours of more than 7000 British civil servants without known heart disease were obtained between 1991 and 1993, with follow-up through 2004. The primary endpoint was incident CHD, defined as coronary-related death or nonfatal myocardial infarction.
After adjusting for Framingham risk score, participants with workdays of 10 hours (hazard ratio, 1.45) or ≥11 hours (HR, 1.67) had higher rates of CHD than those with workdays of 7 to 8 hours. The addition of working hours to th…