Loading...
Diabetes typically causes a symmetric, distal, predominantly sensory neuropathy. Much less common is diabetic amyotrophy, an often asymmetric, relatively acute, painful neuropathy dominated by lower-limb muscle weakness. This condition — also called diabetic lumbosacral radiculoplexus neuropathy (DLRPN) — is thought to reflect ischemic microvascular injury that affects nerve roots and peripheral nerves. Now, Mayo Clinic researchers present 23 diabetic patients (22 with type 2 diabetes) who had a painless variant of this disorder, which they call “painless diabetic motor neuropathy.”
Median duration of diabetes was 5 years, but the neurological presentation coincided with a first recognition of diabetes in seven cases. Glycemic control was ge…