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Many approaches to lifestyle modification in patients with diabetes result in weight loss and better glycemic control. Researchers looked beyond those outcomes to improvements in mobility. About 5000 adults with type 2 diabetes (mean age, 59; 60% women; mean body-mass index, 36 kg/m2) were randomized to follow an intensive lifestyle-modification program or a diabetes education-and-support program.
By 1 year, mean weekly calorie expenditure was significantly greater in the intensive-intervention group than in the control group (881 kcal vs. 99 kcal), as was mean percentage weight loss (6% vs. 1%). At 4 years, according to a multicomponent annual assessment of mobility-related disability, the percentage of intensive-intervention recipients wit…