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The surgical management of patients with endometrial cancer remains a hotly debated topic. To address the role of lymphadenectomy, investigators assessed survival in 671 Japanese patients (median age, 56) who underwent either pelvic lymphadenectomy only or combined pelvic and para-aortic lymphadenectomy from 1986 to 2004. Risk for disease recurrence was assigned based on tumor characteristics (stage, grade, histology, and lymphatic-vascular space invasion); 61% of patients were classified as being at intermediate or high risk, and these patients also were offered adjuvant radiotherapy or chemotherapy.
After median follow-up of approximately 90 months, overall survival was longer in patients who underwent combined pelvic and para-aortic lymph…