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Journal Watch Oncology and Hematology physician-editor Michael E. Williams attended the recent American Society of Hematology meeting in Orlando, Florida. Here he reports some of the highlights.
A current standard of care for advanced-stage, asymptomatic, nonbulky follicular lymphoma (FL) is to withhold antilymphoma therapy until progressive disease or symptoms warrant its use (a watch-and-wait strategy). To assess the value of immunotherapy with rituximab for this condition, investigators randomized 462 patients to a watch-and-wait strategy, a basic rituximab strategy (375 mg/m2/week for 4 weeks), or that same rituximab strategy followed by rituximab maintenance every 2 months for 2 years …