Smoking Increases the Risk for Prostate Cancer Recurrence and Mortality

The increase in risk was seen only among men who were current or recent smokers at the time of diagnosis.

Several studies have suggested that cigarette smoking increases the risk for prostate cancer mortality, but most of these studies were relatively small. Now, researchers have evaluated this association as well as the link between smoking and prostate cancer recurrence in a large U.S. prospective cohort study (the Health Professionals Follow-Up Study).

More than 50,000 men were enrolled in the cohort in 1986 and asked to complete detailed questionnaires every 2 years about various lifestyle factors, including current and past cigarette use, and any new medical diagnoses. The present analysis focused on 5366 men who reported prostate cancer diagnoses between 1986 and 2006.

During follow-up, there were 878 biochemical recurrences (defined by an …

Reviewing Author

Robert Dreicer, MD, MS, FACP

Disclosures

Consultant/Advisory BoardAstellas; Aveo; Bayer; Gilead; Merck; Pfizer; Propella; Macrogenics

Editorial BoardsCurrent Urology Reports

Robert Dreicer, MD, MS, FACP

Disclosures

Consultant/Advisory BoardAstellas; Aveo; Bayer; Gilead; Merck; Pfizer; Propella; Macrogenics

Editorial BoardsCurrent Urology Reports

Smoking Increases the Risk for Prostate Cancer Recurrence and Mortality

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Reviewing Author