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Obesity and physical inactivity may increase the risk of developing colorectal cancer, potentially mediated through hyperinsulinemia. Moreover, recent studies of stage III colon cancer survivors indicate that reduced physical activity and consumption of a Western diet may increase the risk of colon cancer recurrence.
Now, investigators have conducted a prospective, observational study to evaluate the impact of specific dietary glycemic load and total carbohydrate intake on colon cancer recurrence and survival in a cohort of stage III colon cancer patients enrolled in the Cancer and Leukemia Group B 89803 trial. A total of 1011 patients completed questionnaires regarding diet and lifestyle habits midway through adjuvant chemotherapy and 6 mon…