Enterovirus Type 71 in the U.S.

Enteroviral infection in the pediatric population most commonly manifests as a minor viral infection with or without rash; herpangina; or hand, foot, and mouth disease. Less common but more severe manifestations include myocarditis, aseptic meningitis, and encephalitis. Recently, outbreaks of enterovirus serotype 71 (EV71) have caused substantial morbidity and mortality in Asia. Now, researchers describe an EV71 outbreak in Denver involving 16 patients from 2003 through 2005.

In a retrospective chart review, researchers identified eight children each in 2003 and in 2005 who were hospitalized for EV71-associated disease. About half were aged 6 months or younger. All children with EV71 had central nervous system infection, and five had acute f…