ADHD Medications Do Not Worsen Tics

Some might actually eliminate tics.

About 20% of children with attention-deficit/hyperactivity disorder (ADHD) have coexisting tics, but the association between stimulant medications and tics in children with ADHD remains controversial. Clinicians often ask about the safety of ADHD medications in patients with tics. Therefore, researchers conducted a meta-analysis of data from nine randomized, placebo-controlled trials that involved 477 children (age range, 5–17 years).

Methylphenidate, α₂ agonists (guanfacine and clonidine), atomoxetine, and desipramine improved ADHD behaviors in children and youths with coexisting tics. None of these medicines worsened tic severity. Improvements were statistically significant with α₂ agonists and atomoxetine; treatment with methylphenidate w…

Reviewing Author

Martin T. Stein, MD

Disclosures

Consultant / Advisory boardPearson Neuroscience Advisory Board

Speaker’s bureauAmerican Academy of Pediatrics

RoyaltiesElsevier, Inc.

Editorial boardsJournal of Developmental and Behavioral Pediatrics

Martin T. Stein, MD

Disclosures

Consultant / Advisory boardPearson Neuroscience Advisory Board

Speaker’s bureauAmerican Academy of Pediatrics

RoyaltiesElsevier, Inc.

Editorial boardsJournal of Developmental and Behavioral Pediatrics