Separating the Effects of Early Linear Growth and Relative Weight Gain on Adult Health

In low- and middle-income countries, overemphasis on rapid weight gain after age 2 years could increase the health burden in adults.

Health policy in low- and middle-income countries has focused on rapid correction of growth failure in early life. However, rapid weight gain in early life increases risk for adverse adult health outcomes. In a pooled analysis of prospective birth cohorts (8362 participants) from Brazil, Guatemala, India, the Philippines, and South Africa, researchers examined how independent measures of linear growth and weight gain are associated with adult outcomes.

Higher birth weight and faster linear growth were significantly associated with adult body-mass index (BMI) >25 kg/m² and reduced risk for both short stature and not completing secondary school. Faster weight gain (independent of linear growth) at age 2 years and mid-childhood increased risk f…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Separating the Effects of Early Linear Growth and Relative Weight Gain on Adult Health

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Reviewing Author