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Women with a diagnosis of unilateral breast cancer have increased risk for developing cancer in the other breast. Investigators at 25 U.S. sites assessed the role of contralateral breast magnetic resonance imaging in women with recently diagnosed breast cancer who had had normal clinical and mammographic findings in the contralateral breast within 90 days of study enrollment. Contralateral breast MRI was performed no later than 2 months after diagnosis, and cancer status was followed for 1 year after the study MRI.
Of the 969 evaluable women (mean age, 53 years; 91% white; 80% with no family history of breast cancer), 121 women underwent recommended biopsies based on positive MRI findings. As a result, 30 tumors were detected, including 18 i…