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The projected incidence of new cancer cases in the U.S. in 2007 is almost 1,500,000; about 4% of these will occur in patients younger than 35.1,2 By 2010, as many as 1 in 250 patients will have survived childhood cancer.3 As more children and young adults survive malignancies, cancer and its treatment will continue to add to the problem of infertility.
The probability of a female developing invasive cancer from birth to age 39 is about 2%.1 More women are surviving malignancies because of improvements in cancer diagnosis and treatment, but these lifesaving technologies come at a price: Infertility is a common complication of cancer therapy in young women. Modified chemotherapy regimens and surgical techniques as well as adjunctive treatments…