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Studies focusing on fasting triglyceride (TG) levels and cardiovascular (CV) risk have yielded inconsistent and controversial findings. In this prospective study, investigators stratified 28,000 initially healthy participants in the Women’s Health Study into tertiles according to fasting and nonfasting TG levels and evaluated the incidence of CV events (myocardial infarction, stroke, coronary revascularization, or CV death) during a median follow-up of approximately 11 years.
About 1000 participants experienced a first CV event during follow-up. Adjusting for total cholesterol and HDL-C and for indicators of insulin resistance (diabetes, BMI, and high-sensitivity C-reactive protein) reduced the association between fasting TG levels and CV ev…